Antimicrobial Activity of Calotropis gigantea against Staphylococcus aureus: Eco-Friendly Management

Abstract

Calotropis gigantea (Madaar) Linn. is a potent medicinal herb that has active compounds in the form of alkaloids, glycosides, lactones, and steroids. All these active compounds have immune-modulatory and physiological roles of different types; the plant is also reported as effective in treating skin, digestive, respiratory, circulatory, and neurological disorders and was used to treat fevers, elephantiasis, nausea, vomiting, and diarrhea. In this study, the phytochemical and the zone of inhibition was measured in C. gigantea L. It proves that C. gigantea L. is more effective against Staphylococcus aureus. Aqueous extract of C. gigantea L. was extracted by the aqueous method. In the qualitative phytochemical analysis presence of various secondary metabolites were found as alkaloids, flavonoids, tannins, and saponin. In the quantitative analysis, carbohydrate was found in C. gigantea L. about concentration is found (470 μg/mL). Antimicrobial activity was also quite good against S. aureus. The study demonstrates that the C. gigantea L. contains the presence different of bioactive compounds indicated a potent antimicrobial activity of C. gigantea L. against S. aureus so that we called as eco-friendly management.